Biology Acellular Life UHS 2023
PMDC Verified Question 34 of 70
The provirus of HIV is structurally and chemically made up of?
A
dsRNA
B
ssDNA
C
dsDNA
D
ssRNA
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option C: dsDNA
Concept:

The term "provirus" refers to the specific state of the viral genome after it has been integrated into the host's chromosome.

Solution:

  • Once HIV enters a host cell, its single-stranded RNA (ssRNA) genome is reverse-transcribed into double-stranded DNA (dsDNA).
  • This dsDNA is then transported into the nucleus and spliced into the host's DNA by the enzyme integrase. In this integrated state, it is termed a provirus.


Why other options are incorrect:

  • ssRNA: This is the structure of the free viral genome, not the integrated provirus.
  • ssDNA / dsRNA: These are not intermediates in the HIV integration pathway.

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