Biology Acellular Life KMU 2024
PMDC Verified Question 15 of 70
Where are the enzymes required for the replication of HIV virus located?
A
Surrounding the viral core
B
In the protein spikes
C
Outside the capsid
D
Inside the capsid
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option D: Inside the capsid
Concept:

Retroviruses must physically carry their replication enzymes into the host cell because the host lacks RNA-dependent DNA synthesis machinery.

Solution:

  • HIV packages its three essential replication enzymes (reverse transcriptase, integrase, and protease) directly inside the capsid, alongside its viral RNA genome.
  • This ensures that the moment the capsid uncoats in the host cytoplasm, the enzymes are immediately available to begin reverse transcription.


Why other options are incorrect:

  • In the protein spikes / Outside the capsid: Enzymes placed outside the protective core would be unstable and useless during the intracellular replication phase. Spikes are strictly for attachment.

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