Biology Bioenergetics NUMS 2024
PMDC Verified Question 23 of 67
Fats and proteins can be used as respiratory fuel. Which of the following serves as common molecule produced through their catabolism?
A
Acetyl CoA
B
Pyruvate
C
G3P
D
Lactate
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option A: Acetyl CoA
Concept:

Metabolic pathways are interconnected. Carbohydrates, lipids, and proteins can all feed into cellular respiration at various intersection points.

Solution:

  • When fats are broken down (beta-oxidation of fatty acids) and proteins are deaminated, they must enter the central respiratory pathway to generate ATP.
  • The universal "crossroads" molecule that links the catabolism of carbohydrates, fats, and most amino acids directly into the Krebs cycle is Acetyl CoA.


Why other options are incorrect:

  • While some amino acids can form pyruvate, fatty acids cannot. Acetyl CoA is the exclusively common denominator.
  • G3P is specific to glycolysis.
  • Lactate is an end-product of anaerobic fermentation.

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