Biology Biomolecules NUMS 2023
PMDC Verified Question 53 of 142
Which of the following protein establishes the matrix of bone & cartilage?
A
Elastin
B
Collagen
C
Keratin
D
Histone
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option B: Collagen
Concept:

The structural integrity of skeletal connective tissue relies on a highly specialized extracellular fibrous protein network.

Solution:

  • Collagen is the primary structural protein of the extracellular matrix in all connective tissues.


  • It forms tough, inextensible fibers that act as the physical scaffold (matrix) into which calcium phosphate is deposited to form rigid bone, or proteoglycans are deposited to form flexible cartilage.


Why other options are incorrect:

  • Keratin: Structural protein, but strictly for external appendages like hair, nails, and epidermis, not internal skeletal matrices.


  • Elastin: Provides elasticity to lungs and arteries, not rigid skeletal structure.


  • Histone: A nuclear globular protein used to spool DNA.

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