Biology Biotechnology KMU 2025
PMDC Verified Question 55 of 65
In somatic cell hybridization, which two cells are fused to produce monoclonal antibodies?
A
T-cells and nerve cells
B
T-cells and liver cells
C
B-lymphocytes and spleen cells
D
B-lymphocytes and macrophages
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option C: B-lymphocytes and spleen cells
Concept:

Hybridoma technology cell fusion partners.

Solution:

Somatic cell hybridization merges antibody-secreting B-lymphocytes (isolated from immunized animal spleen tissue) with immortal myeloma cells to generate hybridomas capable of continuous monoclonal antibody production.

Why other options are incorrect:

  • T-cells and nerve cells: T-cells function in cell-mediated immunity without producing soluble antibodies; nerve cells lack antibody production capacity.


  • T-cells and liver cells: Hepatocytes and T-cells do not express immunoglobulin antibody molecules.


  • B-lymphocytes and macrophages: Macrophages perform antigen phagocytosis and processing; they do not secrete monoclonal antibodies.

Quality & Fidelity Assurance: Every question on BeambePrep is rigorously curated against the official PMDC syllabus with zero filler, zero out-of-syllabus content, and zero typos. When an authentic past paper originally contained a historical mistake or ambiguity from the examining board (such as UHS or NUMS), BeambePrep faithfully reflects the original paper while detailing the nuance and scientific consensus in the autopsy above.

Want to solve full-length papers under timed exam conditions?

Practice with zero-scroll lockdown sprints, dynamic latency zone timers, live peer selection telemetry, and the automated Amber mistake recovery loop.