Biology Biotechnology PMDC Conceptual Practice
PMDC Verified Question 28 of 65
Transgenic goats produce antithrombin III, which is secreted in their:
A
Milk
B
Urine
C
Blood
D
Saliva
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option A: Milk
Concept:

Tissue-specific expression of recombinant proteins in transgenic animals.

Solution:

By placing the human antithrombin III gene under the regulatory control of a mammary-gland specific promoter (such as beta-casein), transgenic goats secrete antithrombin III directly into their milk.

Why other options are incorrect:

  • Urine: Requires kidney-specific filtration promoters; less suited for high-yield harvest than milk.


  • Blood: Expressing bioactive therapeutic proteins systemically in animal blood can compromise host physiological health.


  • Saliva: Expresses low protein concentrations compared to specialized mammary gland secretion.

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