Biology Biotechnology PMDC Conceptual Practice
PMDC Verified Question 30 of 65
Monoclonal antibodies are produced by fusing B-lymphocytes with:
A
T-cells
B
Macrophages
C
Myeloma cells
D
Fibroblasts
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option C: Myeloma cells
Concept:

Hybridoma technology for monoclonal antibody production.

Solution:

Hybridomas are created by fusing short-lived antibody-producing B-lymphocytes with cancerous, immortal myeloma cells, granting indefinite culture capacity.

Why other options are incorrect:

  • T-cells: Responsible for cell-mediated immunity; do not secrete soluble antibody molecules.


  • Macrophages: Phagocytic antigen-presenting cells that do not synthesize immunoglobulins.


  • Fibroblasts: Structural connective tissue cells that do not synthesize antibody proteins.

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