Biology Cell NUMS 2024
PMDC Verified Question 16 of 143
Follow the route of pepsinogen secreted by zymogen cells:
A
SER → RER → Golgi complex → Secretory vesicles
B
RER → SER → Golgi complex → Secretory vesicles
C
SER → Mitochondria → Golgi complex → Secretory vesicles
D
Golgi complex → RER → SER → Secretory vesicles
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option B: RER → SER → Golgi complex → Secretory vesicles
Concept: The endomembrane system operates as a sequential assembly and shipping line for proteins.

Solution: Pepsinogen is a protein. Its correct secretory pathway is:
1. Synthesized on ribosomes of the Rough ER (RER).
2. Transitions through the Smooth ER (SER) where transport vesicles bud off.
3. Received and processed by the Golgi complex.
4. Packaged into Secretory vesicles that fuse with the plasma membrane.

Distractor Autopsy: Proteins are not synthesized by the SER, so starting there is incorrect. The Golgi is the final processor, not the starting point.

Quality & Fidelity Assurance: Every question on BeambePrep is rigorously curated against the official PMDC syllabus with zero filler, zero out-of-syllabus content, and zero typos. When an authentic past paper originally contained a historical mistake or ambiguity from the examining board (such as UHS or NUMS), BeambePrep faithfully reflects the original paper while detailing the nuance and scientific consensus in the autopsy above.

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