Biology Chemical Coordination LUMHS 2014
PMDC Verified Question 49 of 50
[LUMMHC-2014] Destruction of all beta cells in the pancreas would cause:
A
Insulin secretion to stop and an increase in blood glucose
B
Glucagon secretion to stop and a decrease in blood glucose
C
Glucagon secretion to stop and an increase in blood glucose
D
Insulin secretion to stop and a decrease in blood glucose
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option A: Insulin secretion to stop and an increase in blood glucose
Concept:

The Islets of Langerhans in the pancreas contain beta cells, which are exclusively responsible for insulin production.

Solution:

  • Insulin is the only hormone capable of lowering blood glucose by facilitating its uptake into skeletal muscle and adipose tissue.


  • If all beta cells are destroyed (as occurs in autoimmune Type 1 Diabetes Mellitus), insulin secretion stops completely. Consequently, glucose becomes trapped in the bloodstream, leading to a massive increase in blood glucose.


Why other options are incorrect:

Alpha cells produce glucagon, so their destruction would affect glucagon, not beta cell destruction.

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