Biology Digestion/Nutrition MDCAT 2017
PMDC Verified Question 36 of 48
Enzyme pepsin acts on which of the following substrate to produce the respective product?
A
Substrate: Proteins → Product: Polypeptides
B
Substrate: Polypeptide → Product: Dipeptides
C
Substrate: Fats → Product: Fatty acids / glycerol
D
Substrate: Proteins → Product: Amino acids
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option A: Substrate: Proteins → Product: Polypeptides
Concept:

Pepsin is an endopeptidase that operates in the highly acidic environment of the stomach to begin the chemical breakdown of dietary proteins.

Formula:

N/A

Solution:

  • Pepsin acts on large, intact Proteins.
  • It cleaves internal peptide bonds, reducing these massive protein molecules into smaller fragments known as Polypeptides and peptones.
  • It does not complete the digestion down to individual amino acids.


Why other options are incorrect:

Complete breakdown to dipeptides and free amino acids requires pancreatic enzymes (like trypsin/chymotrypsin) and intestinal brush border peptidases. Fats are digested by lipases, not pepsin.

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