Biology Digestion/Nutrition MDCAT 2015
PMDC Verified Question 44 of 48
Trypsinogen is activated to trypsin by:
A
HCl
B
Mucus
C
Enterokinase
D
Gastrin
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option C: Enterokinase
Concept:

Pancreatic proteases are secreted in inactive zymogen forms to prevent the pancreas from digesting itself. They require a highly specific activator in the duodenum.

Formula:

N/A

Solution:

  • Trypsinogen is an inactive pancreatic enzyme.
  • Upon entering the duodenum, it encounters Enterokinase (also called enteropeptidase), an enzyme embedded in the brush border of the intestinal mucosa.
  • Enterokinase specifically cleaves a peptide segment from trypsinogen, transforming it into the active enzyme trypsin.


Why other options are incorrect:

HCl activates pepsinogen in the stomach, not trypsinogen. Mucus is protective. Gastrin is a stomach hormone.

Quality & Fidelity Assurance: Every question on BeambePrep is rigorously curated against the official PMDC syllabus with zero filler, zero out-of-syllabus content, and zero typos. When an authentic past paper originally contained a historical mistake or ambiguity from the examining board (such as UHS or NUMS), BeambePrep faithfully reflects the original paper while detailing the nuance and scientific consensus in the autopsy above.

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