Biology Digestion/Nutrition ETEA 2023
PMDC Verified Question 14 of 48
Trypsinogen can be activated by the action of:
A
Amylase
B
HCl
C
Glucokinase
D
Enterokinase
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option D: Enterokinase
Concept:

Zymogens require specific biochemical triggers to expose their active sites, preventing auto-digestion of the secreting glands.

Formula:

N/A

Solution:

  • Trypsinogen is produced in the pancreas and secreted into the duodenum.
  • The epithelial cells of the duodenum produce an enzyme called Enterokinase (enteropeptidase).
  • Enterokinase selectively cleaves trypsinogen to form the active protease trypsin, which subsequently activates all other pancreatic zymogens.


Why other options are incorrect:

HCl activates gastric pepsinogen. Amylase digests starch. Glucokinase phosphorylates glucose in glycolysis. None of these activate pancreatic proteases.

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