Concept:Gastric mucosal glands contain specialized epithelial cell types, each dedicated to secreting specific components of gastric juice:
- Chief (Zymogenic) cells: Secrete pepsinogen (the inactive zymogen precursor of pepsin) and gastric lipase.
- Parietal (Oxyntic) cells: Secrete hydrochloric acid (\(\text{HCl}\)) and Castle's intrinsic factor (essential for vitamin \(\text{B}_{12}\) absorption).
- Mucus (Goblet / Neck) cells: Secrete alkaline protective mucus to shield the gastric lining from autodigestion.
- Endocrine (G-cells / Enterochromaffin-like cells): Secrete regulatory hormones like gastrin and histamine.
Solution:- Chief cell → Pepsinogen: Correct biological match.
- Endocrine cell → Hormone (Gastrin): Correct biological match.
- Mucus cell → Mucus: Correct biological match.
- Parietal cell → Pepsin: Mismatched pair. Parietal cells secrete \(\text{HCl}\) and intrinsic factor; pepsin is derived from chief cell pepsinogen. Hence, Option C is the mismatched pair.
Why other options are incorrect:Options A, B, and D represent accurate physiological pairings in human gastrointestinal anatomy.
Quality & Fidelity Assurance:
Every question on BeambePrep is rigorously curated against the official PMDC syllabus with zero filler, zero out-of-syllabus content, and zero typos. When an authentic past paper originally contained a historical mistake or ambiguity from the examining board (such as UHS or NUMS), BeambePrep faithfully reflects the original paper while detailing the nuance and scientific consensus in the autopsy above.