Biology Enzymes ETEA 2023
PMDC Verified Question 40 of 79
The inhibition, in which the inhibitor does not combine directly with the enzyme but binds to the enzyme substrate complex is called:
A
Reversible inhibition
B
Competitive inhibition
C
Non-competitive inhibition
D
Uncompetitive inhibition
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option D: Uncompetitive inhibition
Concept:

Inhibitors are classified by exactly when and where they bind to the enzyme during the catalytic cycle.

Solution:

  • If an inhibitor only recognizes and binds to the enzyme after the substrate has already attached (forming the Enzyme-Substrate or ES complex), it traps the substrate inside.
  • This highly specific mechanism is strictly defined as Uncompetitive inhibition.
  • It prevents the ES complex from converting into products and cannot be overcome by adding more substrate.


Why other options are incorrect:

Competitive inhibitors bind the free enzyme. Non-competitive inhibitors can bind both the free enzyme and the ES complex. Binding exclusively to the ES complex is the hallmark of uncompetitive inhibition.

Quality & Fidelity Assurance: Every question on BeambePrep is rigorously curated against the official PMDC syllabus with zero filler, zero out-of-syllabus content, and zero typos. When an authentic past paper originally contained a historical mistake or ambiguity from the examining board (such as UHS or NUMS), BeambePrep faithfully reflects the original paper while detailing the nuance and scientific consensus in the autopsy above.

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