Biology Homeostasis PMDC Conceptual Practice
PMDC Verified Question 64 of 99
Which specific nephron tubular segments contain principal cells whose water permeability is regulated by ADH?
A
Distal convoluted tubule and collecting ducts
B
Bowman's capsule and glomerulus
C
Ascending limb of Henle
D
Descending limb of Henle
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option A: Distal convoluted tubule and collecting ducts
Concept: ADH sensitive nephron segments.

Solution: ADH acts specifically on principal cells of the late distal convoluted tubule and collecting ducts to insert aquaporin-2 channels.

Why other options are incorrect:
  • Option B: Glomerular filtration is driven by Starling capillary forces, independent of ADH.

  • Option C: The ascending limb is permanently water-impermeable.

  • Option D: The descending limb is constitutively water-permeable via aquaporin-1.

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