Biology Immunity MDCAT 2015
PMDC Verified Question 94 of 99
Response of body against the transplanted organ is:
A
Homeostatic Response
B
Primary Response
C
Behavioral Response
D
Cell-mediated Response
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option D: Cell-mediated Response
Concept:

Tissue rejection is primarily a function of the cellular branch of the adaptive immune system recognizing foreign MHC markers.

Formula:

None

Solution:

  • A transplanted organ contains cells with non-self Major Histocompatibility Complex (MHC) or HLA antigens.


  • Cytotoxic T-cells identify these foreign cells and directly induce apoptosis (cell death) in the transplanted tissue.


  • This direct cellular attack classifies graft rejection strictly as a cell-mediated response.


Why other options are incorrect:

  • Antibodies (humoral response) play a minor or hyperacute role, but the primary chronic rejection is T-cell mediated.

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