Biology Immunity PMC 2020
PMDC Verified Question 83 of 99
Autoimmune diseases act at the principle of:
A
Self against antigens
B
Self against self
C
Antigen against self
D
Antigen self-destroyed
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option B: Self against self
Concept:

A healthy immune system exhibits "self-tolerance," meaning it ignores the body's own tissues while attacking foreign antigens.

Formula:

None

Solution:

  • In an autoimmune disease, there is a breakdown in immunological tolerance.


  • The body's T-cells and auto-antibodies mistakenly identify the host's own healthy cells as foreign invaders.


  • This results in the immune system actively destroying its own tissues, fundamentally operating on the principle of self against self.


Why other options are incorrect:

  • "Self against antigens" is the normal, healthy immune response.

Quality & Fidelity Assurance: Every question on BeambePrep is rigorously curated against the official PMDC syllabus with zero filler, zero out-of-syllabus content, and zero typos. When an authentic past paper originally contained a historical mistake or ambiguity from the examining board (such as UHS or NUMS), BeambePrep faithfully reflects the original paper while detailing the nuance and scientific consensus in the autopsy above.

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