Biology Immunity KMU 2024
PMDC Verified Question 61 of 99
What directly triggers the activation of natural killer cells?
A
Free radicals
B
Hydrogen peroxide
C
Oxygen
D
Interferons
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option D: Interferons
Concept:

The innate immune system utilizes cytokine signaling to mobilize cellular defenses rapidly.

Formula:

None

Solution:

  • When a host cell is infected by a virus, it synthesizes and secretes warning proteins known as Interferons.


  • These interferons bind to receptors on nearby uninfected cells to boost their defenses.


  • Crucially, interferons act as a chemical distress beacon that directly stimulates and activates nearby Natural Killer (NK) cells to find and destroy the infected host cells.


Why other options are incorrect:

  • Free radicals, hydrogen peroxide, and oxygen are chemicals used during the "respiratory burst" by macrophages and neutrophils to digest phagocytosed bacteria, but they are not the signaling molecules that activate NK cells.

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