Biology Immunity PMDC Conceptual Practice
PMDC Verified Question 11 of 99
The preferred primary target host cells for Human Immunodeficiency Virus (HIV) infection are:
A
CD4+ T-cells
B
Erythrocytes
C
B-lymphocytes
D
Neutrophils
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option A: CD4+ T-cells
Concept: HIV viral tropism and pathogenesis.

Solution: HIV viral surface glycoprotein gp120 binds specifically to the CD4 receptor present predominantly on helper T-cells (CD4+ T-cells) and macrophages, leading to viral entry and destruction of host immune capacity.

Why other options are incorrect:
  • Option B: RBCs lack CD4 surface receptors and nuclei required for viral replication.

  • Option C: B-cells express CD19/CD20 receptors, not high levels of CD4 needed for standard HIV tropism.

  • Option D: Neutrophils lack CD4 target receptors.

Quality & Fidelity Assurance: Every question on BeambePrep is rigorously curated against the official PMDC syllabus with zero filler, zero out-of-syllabus content, and zero typos. When an authentic past paper originally contained a historical mistake or ambiguity from the examining board (such as UHS or NUMS), BeambePrep faithfully reflects the original paper while detailing the nuance and scientific consensus in the autopsy above.

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