Biology Immunity PMDC Conceptual Practice
PMDC Verified Question 28 of 99
In addition to helper CD4+ T-lymphocytes, HIV is well-documented to infect and establish cellular reservoirs in circulating:
A
Neutrophils
B
Eosinophils
C
Basophils
D
Macrophages
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option D: Macrophages
Concept: Host cell susceptibility to HIV.

Solution: Macrophages (and their precursor monocytes) express surface CD4 molecules alongside CCR5 co-receptors, making them major targets and persistent tissue reservoirs for HIV.

Why other options are incorrect:
  • Option A, Option B & Option C: Granulocytes lack the necessary receptor/co-receptor combination (CD4/CCR5) required for productive HIV infection.

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