Biology Immunity PMDC Conceptual Practice
PMDC Verified Question 33 of 99
The immune response primarily responsible for graft rejection following an organ transplantation is the:
A
Humoral immune response
B
Homeostatic response
C
Cell-mediated response
D
Behavioral response
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option C: Cell-mediated response
Concept: Transplantation immunology and graft rejection.

Solution: Graft rejection occurs when host cytotoxic T-lymphocytes recognize foreign human leukocyte antigens (HLA/MHC) on transplanted tissue cells and destroy them through a cell-mediated response.

Why other options are incorrect:
  • Option A: Humoral responses contribute to hyperacute rejection via pre-existing antibodies, but acute primary cellular graft rejection is mediated by T-cells.

  • Option B & Option D: Homeostatic and behavioral responses are physiological and neuro-behavioral adaptations, not adaptive immunological effector pathways.

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