Biology Immunity PMDC Conceptual Practice
PMDC Verified Question 58 of 99
Human Immunodeficiency Virus (HIV) selectively infects and destroys which essential immune regulatory cell population?
A
Helper T-cells (CD4+)
B
Neutrophils
C
Cytotoxic T-cells (CD8+)
D
Eosinophils
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option A: Helper T-cells (CD4+)
Concept: Cellular target of HIV.

Solution: HIV utilizes its envelope protein gp120 to bind to CD4 surface receptors, primarily targeting Helper T-cells. Depletion of CD4+ T-cells impairs both cell-mediated and humoral immunity.

Why other options are incorrect:
  • Option B & Option D: Granulocytes do not express the CD4 receptor needed for standard HIV tropism.

  • Option C: CD8+ cytotoxic T-cells lack CD4 receptors, though their function declines indirectly as CD4+ helper cells are destroyed.

Quality & Fidelity Assurance: Every question on BeambePrep is rigorously curated against the official PMDC syllabus with zero filler, zero out-of-syllabus content, and zero typos. When an authentic past paper originally contained a historical mistake or ambiguity from the examining board (such as UHS or NUMS), BeambePrep faithfully reflects the original paper while detailing the nuance and scientific consensus in the autopsy above.

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