Biology Inheritance / Variation & Genetics UHS 2022
PMDC Verified Question 61 of 94
What happens when an 'Rh' negative woman married to an 'Rh' positive man conceives a child who is 'Rh' positive?
A
Maternal-fetal incompatibility
B
Paternal-fetal incompatibility
C
Cancer of fetus
D
Death of mother
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option A: Maternal-fetal incompatibility
Concept:

Rh incompatibility occurs when the immune system of an Rh-negative mother is exposed to Rh-positive fetal blood cells.

Solution:

  • If an Rh-negative woman carries an Rh-positive fetus, fetal red blood cells can cross the placenta during late pregnancy or birth.
  • The mother's immune system recognizes the Rh antigen as foreign and begins producing Anti-Rh antibodies.
  • In subsequent pregnancies with an Rh-positive fetus, these maternal antibodies can cross the placenta and destroy the fetal red blood cells.
  • This life-threatening condition is known as Erythroblastosis foetalis, or maternal-fetal incompatibility.


Why other options are incorrect:

  • The conflict is between the mother's immune system and the fetus, hence it is maternal, not paternal incompatibility. It does not cause fetal cancer or typically result in the death of the mother.

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