PMDC Verified Question 26 of 94
A change in the structure of a DNA molecule, producing a different allele of a gene, is a:
A
Chromosome mutation
B
Gene mutation
C
Chromosomal aberrations
D
Recombination
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option B: Gene mutation
Concept:

Mutations are broadly classified by the scale at which they alter genetic material (single nucleotide vs. large structural changes).

Solution:

  • A localized change in the fundamental nucleotide sequence of a DNA molecule that alters a specific gene is explicitly called a gene mutation (or point mutation).
  • This structural change directly produces a new or different allele of that specific gene.


Why other options are incorrect:

  • Chromosome mutation / aberration: Refers to massive, macro-level changes affecting large segments of a chromosome (deletions, inversions, polyploidy), not a simple molecular change forming a new allele.
  • Recombination: The reshuffling of existing alleles, not the creation of a fundamentally new allele structure.

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