Biology Inheritance / Variation & Genetics SZABMU 2024 Reconduct
PMDC Verified Question 9 of 94
What is the principle of blood transfusion in donor and recipient respectively?
A
Antibodies of both
B
Antibodies: antigen of recipient
C
Antigen of both
D
Antigen of donor: Antibodies of recipient
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option D: Antigen of donor: Antibodies of recipient
Concept:

Safe blood transfusion relies on preventing an immune reaction that causes red blood cells to clump and undergo hemolysis.

Solution:

  • The core principle of blood transfusion compatibility focuses on the Antigen of the donor and the Antibodies of the recipient.
  • When donor blood is introduced, we must ensure that the recipient's pre-existing antibodies do not recognize the donor's red blood cell antigens as a threat.
  • If the donor has an antigen that matches the recipient's antibodies (e.g., giving Type A blood with A-antigens to a Type B recipient with anti-A antibodies), a fatal immune reaction will occur.


Why other options are incorrect:

  • The donor's antibodies are usually too diluted in the recipient's plasma to cause a severe reaction, making the donor's antigens the primary clinical concern.

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