Chemistry Aldehydes & Ketones DUHS 2023
PMDC Verified Question 22 of 94
Which of the following will give iodoform reaction on the treatment with \( Na_2CO_3 \) & \( I_2 \)?
A
Methanol
B
Acetic acid
C
Acetic anhydride
D
Acetone
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option D: Acetone
Concept:

The Iodoform reaction is a highly specific cleavage reaction that occurs exclusively when a methyl group is adjacent to a carbonyl carbon (\( CH_3-CO- \)).

Solution:

  • The reagents \( Na_2CO_3 \) (a mild base) and Iodine (\( I_2 \)) create the haloform conditions.


  • Acetone (Propanone) has the structure \( CH_3-CO-CH_3 \).


  • Because it contains the required terminal methyl ketone group, it rapidly undergoes triple iodination followed by base cleavage to yield the yellow precipitate of iodoform (\( CHI_3 \)).


Why other options are incorrect:

Methanol lacks the \( CH_3-CH(OH)- \) structure. Acetic acid and acetic anhydride contain the \( CH_3-CO- \) group but are shielded by their resonance and leaving group dynamics (carboxylic acid derivatives do not undergo the haloform reaction).

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