Chemistry Liquids MDCAT 2019
PMDC Verified Question 59 of 73
An inter molecular force of attraction X is relatively stronger than the other inter molecular forces, it stabilizes \( \alpha \)-helix and \( \beta \)-pleated sheets of proteins. The double helical structure of DNA is also stabilized by this force of attraction. Identify X.
A
Dipole-dipole attraction
B
Hydrogen bonding
C
Ionic interactions
D
Van der Waal's Forces
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option B: Hydrogen bonding
Concept:

Macromolecules like proteins and nucleic acids rely on specific, directional intermolecular forces to maintain their complex 3D structures.

Formula:

Not applicable.

Solution:

  • In proteins, the partial positive Hydrogen of the amide group (\( \text{-NH} \)) forms strong interactions with the partial negative Oxygen of the carbonyl group (\( \text{-C=O} \)), stabilizing \( \alpha \)-helices and \( \beta \)-sheets.


  • In DNA, the nitrogenous base pairs (A-T and C-G) strictly connect via the same type of interaction.


  • These directional, relatively strong intermolecular forces are Hydrogen bonds.


Why other options are incorrect:

While Van der Waals and standard dipole forces exist, they are too weak and non-directional to primarily dictate these rigid secondary structures. Ionic interactions form salt bridges but are not the primary backbone stabilizers of these specific motifs.

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