Biology Biomolecules SZABMU 2024
PMDC Verified Question 19 of 142
The bond between hydroxyl group of carboxylic group of one amino acid and hydrogen of amino group of second amino acid with release of water molecule is called?
A
Glycosidic bond
B
Peptide bond
C
Hydrogen bond
D
Disulfide bridge
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option B: Peptide bond
Concept:

The primary structural backbone of all proteins is formed by a highly specific, repeating covalent linkage.

Solution:

  • When two amino acids approach each other, a condensation reaction occurs.


  • The \(-OH\) is stripped from the carboxyl group of the first amino acid, and an \(-H\) is stripped from the amino group of the second.


  • This expels a water molecule and forms a strong, covalent Carbon-Nitrogen bond specifically bridging the two monomers.


  • In biochemistry, this specific C-N linkage between amino acids is exclusively called a Peptide bond.


Why other options are incorrect:

  • Glycosidic bond: Formed between two sugars, not amino acids.


  • Disulfide bridge: Formed between the sulfur atoms of two distant Cysteine R-groups to stabilize 3D folding, not to link the main backbone.


  • Hydrogen bond: A weak physical attraction, not a strong covalent reaction releasing water.

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