Biology Biomolecules SZABMU 2024
PMDC Verified Question 20 of 142
Which of the following does not have a quaternary structure?
A
Antibodies
B
Hemoglobin
C
DNA polymerase III
D
Myoglobin
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option D: Myoglobin
Concept:

Quaternary structure only exists if a functional protein requires multiple, separate polypeptide chains aggregating together.

Solution:

  • Myoglobin is the oxygen-storing protein found exclusively in muscle tissue.


  • Structurally, it consists of just a single, highly folded polypeptide chain (containing one heme group).


  • Because it is only a single chain, it functionally maxes out at the Tertiary level of structure. It physically does not have a Quaternary structure.


Why other options are incorrect (they DO have Quaternary structure):

  • Hemoglobin: Classic tetramer consisting of exactly 4 separate chains (2 alpha, 2 beta).


  • Antibodies: Complex Y-shaped molecules consisting of 4 chains (2 heavy, 2 light).


  • DNA Polymerase III: A massive, multi-subunit enzymatic complex (holoenzyme) requiring several different chains to function together.

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