Biology Immunity NUMS 2024
PMDC Verified Question 68 of 99
Which of the following type of T-cells are required for the activation of B-cells?
A
Helper T-cells
B
Cytotoxic T-cells
C
Suppressor T-cells
D
Memory T-cells
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option A: Helper T-cells
Concept:

The adaptive immune system requires a "two-key" system to prevent accidental autoimmune activation; B-cells usually cannot mount a full response alone.

Formula:

None

Solution:

  • When a naive B-cell encounters its specific antigen, it engulfs it and displays pieces of it on its surface via MHC-II molecules.


  • However, to undergo rapid clonal expansion and become plasma cells, the B-cell requires chemical permission (interleukins).


  • This permission is granted by Helper T-cells (CD4+ cells) that recognize the displayed antigen and bind to the B-cell, officially activating it.


Why other options are incorrect:

  • Cytotoxic T-cells: Kill infected cells directly.


  • Suppressor T-cells: Turn off the immune response to prevent tissue damage.

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