Biology 63 Solved Past Papers 2010 to 2024 Archives

Reproduction Past Papers

Solved past paper MCQs for Reproduction from official UHS, NUMS, SZABMU, DUHS, and KMU examinations. Includes verified distractor autopsies and step-by-step cognitive explanations.

Boards Included: AJK BUMHS DUHS ETEA MDCAT NUMS PMC SZABMU UHS
Live Exam Simulation

Want to test these 63 questions against a real-time exam countdown with anti-cheat Leaderboard scoring?

Launch in Swarm Mode
PRINT EDITION 100% Toner-Friendly • 0% Heavy Black Blocks

Download Solved Reproduction Past Papers (Print Edition)

Official printable A4 booklet containing all 63 verified past paper MCQs with unbroken options, 5-column rapid answer key, and Propolis cognitive error autopsies.

Interactive Mode:
#1 of 63 UHS 2024
Permalink
Fluid secreted by sertoli cells provides liquid medium, protection and nourishment to:
A
Oocyte
B
Sperms
C
Polar body
D
Spermatogonia
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

Sertoli cells act as "nurse cells" to shepherd the development of male gametes in the harsh internal environment of the testes.

Solution:

  • Within the seminiferous tubules, spermatogonia undergo meiosis and differentiation to become mature gametes.


  • The Sertoli cells surround these developing cells, providing a protective blood-testis barrier, secreting fructose-rich fluids for nourishment, and establishing a liquid medium.


  • Ultimately, this entire supportive architecture is designed to nourish and protect the developing sperms (spermatozoa).


Why other options are incorrect:

Oocytes and polar bodies belong exclusively to female oogenesis. While spermatogonia are present, the functional target of this protection and eventual transport medium is the fully differentiated sperms.
#2 of 63 SZABMU 2024
Permalink
In humans' testis, the spermatozoa are present in:
A
Seminiferous tubules
B
Epididymis
C
Sertoli cells
D
Interstitial cells
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

Although generated in the tubules, structurally mature sperm (spermatozoa) are primarily stored in a specialized duct system.

Solution:

  • Spermatogenesis produces spermatids, which undergo spermiogenesis inside the seminiferous tubules.


  • However, these cells are swept out of the testis almost immediately once fully formed.


  • They arrive in the epididymis (a structure tightly coiled against the testis), where the vast majority of mature spermatozoa are actually stored, concentrated, and acquire motility until ejaculation.


Why other options are incorrect:

Seminiferous tubules primarily contain developing stages (spermatocytes, spermatids). Interstitial cells are outside the tubules. Sertoli cells nurse the sperm but don't store the final spermatozoa payload.
#3 of 63 SZABMU 2024 Reconduct
Permalink
Select the mismatched pair:
A
Seminal vesicle - Junction of sperm duct and ejaculatory duct
B
Prostate gland - Encircles urethra
C
Ejaculatory duct - Enters the testis
D
Bulbourethral gland - Junction of ejaculatory duct and urethra
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

The male reproductive tract is a one-way path from the testes leading outwards.

Solution:

  • Let's evaluate the anatomy of the ducts:


  • The vas deferens leaves the testis. It merges with the duct of the seminal vesicle to form the ejaculatory duct.


  • This ejaculatory duct then passes through the prostate and enters the urethra.


  • Therefore, the statement that the ejaculatory duct "enters the testis" is completely backward anatomically, making it the mismatched pair.


Why other options are incorrect:

The seminal vesicle merges to form the ejaculatory duct. The prostate gland classically encircles the upper portion of the urethra. The bulbourethral (Cowper's) glands sit below the prostate near the urethral junction.
#4 of 63 SZABMU 2024 Reconduct
Permalink
Pick the correct event of luteal phase/secretory phase:
A
Increased secretion of progesterone
B
Increased secretion of FSH
C
Increased secretion of LH
D
Increased secretion of estrogen
View Answer & Propolis Autopsy
Correct Key: Option A Diagnostic Explanation
Concept:

The defining characteristic of the second half of the menstrual cycle is uterine preparation for pregnancy.

Solution:

  • The luteal phase corresponds directly to the secretory phase in the uterus.


  • During this time, the corpus luteum dominates ovarian function.


  • Its primary physiological action is the increased secretion of progesterone, which halts endometrial growth and stimulates the uterine glands to secrete glycogen-rich fluids.


Why other options are incorrect:

FSH and LH are suppressed by negative feedback during the luteal phase. While estrogen is secreted, its major peak occurs during the preceding follicular/proliferative phase, making progesterone the defining "increased" hormone of the luteal phase.
#5 of 63 SZABMU 2024 Reconduct
Permalink
Which of the following diseases is sexually transmitted?
A
Tuberculosis
B
AIDS
C
Dengue fever
D
Cholera
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

Pathogens are classified by their primary vectors and modes of transmission (e.g., airborne, waterborne, bloodborne/sexual).

Solution:

  • AIDS (Acquired Immunodeficiency Syndrome) is caused by the Human Immunodeficiency Virus (HIV).


  • HIV is transmitted through the direct exchange of bodily fluids, most commonly via unprotected sexual contact, making it a classic sexually transmitted disease (STD).


Why other options are incorrect:

Tuberculosis is transmitted via airborne respiratory droplets. Dengue fever is transmitted by mosquito vectors. Cholera is a waterborne intestinal infection.
#6 of 63 SZABMU 2024 Reconduct
Permalink
In human males, inhibin hormone is produced by:
A
Leydig cells
B
Hensen's node cells
C
Sertoli cells
D
Interstitial cells
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

The testis utilizes a specialized negative feedback mechanism to prevent the overproduction of sperm.

Solution:

  • Inside the seminiferous tubules, Sertoli cells facilitate sperm maturation.


  • When the rate of spermatogenesis is too high, these Sertoli cells release a peptide hormone called inhibin.


  • Inhibin travels to the anterior pituitary and specifically suppresses the release of FSH, slowing down sperm production.


Why other options are incorrect:

Leydig cells (also called interstitial cells) produce testosterone, which feeds back to inhibit LH, not primarily FSH. Hensen's node is an embryonic organizer structure.
#7 of 63 UHS 2024
Permalink
Female reproductive system consists of all of the followings EXCEPT:
A
Ovaries
B
Oviduct
C
Cervix
D
Seminiferous tubules
View Answer & Propolis Autopsy
Correct Key: Option D Diagnostic Explanation
Concept:

Male and female reproductive systems utilize completely distinct anatomical sites for gametogenesis.

Solution:

  • The female reproductive system includes the ovaries (gamete production), oviducts (fertilization site), uterus, cervix, and vagina.


  • Seminiferous tubules are the structural and functional units of the testes, exclusively responsible for spermatogenesis. They are unequivocally a part of the male reproductive system.


Why other options are incorrect:

Ovaries, oviduct, and cervix are all defining anatomical structures of the human female reproductive tract.
#8 of 63 SZABMU 2024
Permalink
Which of the following gives rise to first polar body?
A
Oogonium
B
Oocyte
C
Primary oocyte
D
Secondary oocyte
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

Oogenesis utilizes highly unequal cytokinesis to preserve cytoplasm for the viable ovum.

Solution:

  • A diploid primary oocyte undergoes Meiosis I.


  • To ensure the resulting egg has enough nutrients and machinery to support an early embryo, the cell divides its cytoplasm highly unequally.


  • It produces one large secondary oocyte and one tiny, non-functional cell consisting mostly of genetic waste, called the first polar body.


Why other options are incorrect:

The secondary oocyte undergoes Meiosis II to produce the second polar body. Oogonia only undergo mitosis to become primary oocytes.
#9 of 63 SZABMU 2024
Permalink
The ovulation in human females takes place on:
A
6th day after first day of menstruation
B
10th day after first day of menstruation
C
14th day after first day of menstruation
D
27th day after first day of menstruation
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

Clinical calculations for the menstrual cycle always begin with Day 1 as the first day of bleeding.

Solution:

  • In a standardized, idealized 28-day menstrual cycle, the follicular phase lasts approximately two weeks.


  • Driven by the mid-cycle LH surge, the Graafian follicle ruptures.


  • This event, ovulation, reliably occurs right in the middle of the cycle, which is the \(14\text{th}\) day after the first day of menstruation.


Why other options are incorrect:

Days 6-10 are part of the follicular/proliferative phase where the follicle is still growing. Day 27 is the very end of the luteal phase, just prior to the onset of the next menses.
#10 of 63 NUMS 2024
Permalink
Choose the mismatched pair:
A
Graffian follicle – Progesterone
B
ICSH – Interstitial cell
C
Estrogen – Inhibits FSH
D
LH – Ovulation
View Answer & Propolis Autopsy
Correct Key: Option A Diagnostic Explanation
Concept:

Hormone production shifts entirely based on the pre- vs. post-ovulatory state of the follicle.

Solution:

  • Let's analyze the pairs:


  • A. Graafian follicle – Progesterone: This is MISMATCHED. The Graafian (pre-ovulatory) follicle primarily secretes estrogen. It only begins secreting progesterone after it ruptures and transforms into the corpus luteum.


  • B. ICSH stimulates interstitial cells to produce testosterone. (Correct pair)


  • C. Estrogen provides negative feedback to inhibit FSH. (Correct pair)


  • D. LH surge triggers ovulation. (Correct pair)


Why other options are incorrect:

Because options B, C, and D represent factual, core biological relationships, option A is the only biologically incorrect association.
#11 of 63 NUMS 2024
Permalink
If reproductive cycle of a female starts on 10th of July, the ovulation is most likely to occur on:
A
1st august
B
28th of July
C
24th of July
D
5th August
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

Mathematical calculation of cycle events relies on adding the standard follicular phase duration to the onset date.

Solution:

  • The reproductive cycle "starts" on Day 1, which corresponds to July 10th.


  • In a normal 28-day cycle, ovulation occurs on exactly Day 14.


  • To calculate the date: \(10 + 14 = 24\).


  • Therefore, ovulation is most likely to occur on the 24th of July.


Why other options are incorrect:

July 28th would be Day 18. August dates would push deep into the luteal phase or the next menstrual cycle.
#12 of 63 NUMS 2024
Permalink
Which of the following would be produced as a result of reduction division during gametogenesis?
A
Oogonium
B
Primary oocyte
C
Primary spermatocyte
D
Secondary oocyte
View Answer & Propolis Autopsy
Correct Key: Option D Diagnostic Explanation
Concept:

Reduction division refers specifically to Meiosis I, where homologous chromosomes are separated to cut the ploidy level in half (diploid to haploid).

Solution:

  • Oogonia and primary spermatocytes/oocytes are all diploid (\(2n\)) and are produced via mitosis or growth, not reduction.


  • A primary oocyte undergoes Meiosis I (the reduction division).


  • This division physically results in two haploid (\(n\)) cells: a tiny first polar body and a large secondary oocyte.


Why other options are incorrect:

Primary oocytes and spermatocytes are the substrates entering the reduction division, not the products. Oogonia are stem cells that have never entered meiosis.
#13 of 63 SZABMU 2024
Permalink
Which of the following STD affect \(T_4\) lymphocytes?
A
AIDS
B
Syphilis
C
Genital Herpes
D
Gonorrhea
View Answer & Propolis Autopsy
Correct Key: Option A Diagnostic Explanation
Concept:

Certain viruses are highly specific, possessing surface proteins that bind only to specific receptors on human immune cells.

Solution:

  • AIDS (Acquired Immunodeficiency Syndrome) is the late-stage disease caused by HIV.


  • HIV specifically uses the CD4 receptor to enter host cells.


  • The primary cells expressing this receptor are helper T-cells, historically referred to as \(T_4\) lymphocytes (or \(CD4^+\) T-cells). The progressive destruction of these \(T_4\) cells leads to systemic immune failure.


Why other options are incorrect:

Syphilis, Genital Herpes, and Gonorrhea primarily target epithelial cells and mucous membranes in the urogenital tract. They do not specifically infect or systematically destroy \(T_4\) lymphocytes.
#14 of 63 UHS 2024
Permalink
Which one of the following hormones is responsible for the labor pains in human female at the time of birth of baby?
A
Estrogen
B
Progesterone
C
Oxytocin
D
Corticosteroid
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

Labor requires the sudden, forceful activation of uterine musculature via neuroendocrine signals.

Solution:

  • As a pregnancy reaches full term, the posterior pituitary releases massive amounts of the peptide hormone oxytocin.


  • Oxytocin acts directly on the myometrium of the uterus, initiating intense, wave-like contractions to push the fetus toward the cervix.


  • These violent muscular contractions are the direct physiological cause of labor pains.


Why other options are incorrect:

Estrogen upregulates oxytocin receptors but doesn't cause the contractions directly. Progesterone actively prevents contractions. Corticosteroids are involved in fetal lung maturation and maternal stress, not the immediate induction of mechanical labor.
#15 of 63 SZABMU 2023
Permalink
In human males, inhibin hormone is produced by:
A
Leydig cells
B
Hensen's node cells
C
Sertoli cells
D
Interstitial cells
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

Testicular function is regulated by distinct feedback mechanisms originating from its different cell types.

Solution:

  • The seminiferous tubules contain "nurse" cells called Sertoli cells that support developing sperm.


  • When the sperm count is high, these Sertoli cells secrete the protein hormone inhibin.


  • Inhibin travels to the pituitary to suppress FSH secretion, acting as a negative feedback "brake" on spermatogenesis.


Why other options are incorrect:

Leydig cells (also known as interstitial cells) produce testosterone, not inhibin. Hensen's node is a structure found during early embryogenesis, unrelated to male endocrinology.
#16 of 63 ETEA 2023
Permalink
The testes are male gonads which are situated outside the abdomen within a skin pouch called:
A
Vas deferens
B
Epididymis
C
Scrotum
D
Vasa efferentia
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

Mammalian spermatogenesis is highly temperature-sensitive and requires an environment cooler than core body temperature.

Solution:

  • To maintain optimal conditions for sperm development (around \(2^{\circ}\text{C}\) to \(3^{\circ}\text{C}\) lower than normal body temperature), the testes descend outside the abdominal cavity.


  • They are housed in a specialized pendulous sac of skin and smooth muscle called the scrotum.


Why other options are incorrect:

Vas deferens, epididymis, and vasa efferentia are all internal tubular ducts responsible for the transport and storage of sperm, not the external protective skin pouch housing the testes.
#17 of 63 NUMS 2023
Permalink
Leydig cells are responsible for:
A
Testosterone production
B
FSH production
C
Sperm production
D
Testosterone inhibition
View Answer & Propolis Autopsy
Correct Key: Option A Diagnostic Explanation
Concept:

Male characteristics and reproductive functions are driven by androgens synthesized in the testes.

Solution:

  • Leydig cells (interstitial cells) are located in the spaces between the seminiferous tubules in the testes.


  • When stimulated by Luteinizing Hormone (LH) from the pituitary, they synthesize and secrete androgens, primarily testosterone.


  • Testosterone is vital for both spermatogenesis and the maintenance of secondary male sexual characteristics.


Why other options are incorrect:

FSH is produced by the anterior pituitary. Sperm production occurs within the seminiferous tubules by germ cells. Leydig cells produce testosterone, they do not inhibit it.
#18 of 63 SZABMU 2023
Permalink
Which function is not directly performed by ovaries?
A
Progesterone production
B
Estrogen production
C
Ovulation
D
hCG production
View Answer & Propolis Autopsy
Correct Key: Option D Diagnostic Explanation
Concept:

Pregnancy relies on a baton-pass of hormonal control from maternal organs to embryonic organs.

Solution:

  • The ovaries directly perform ovulation (release of the egg) and produce both estrogen (via follicles) and progesterone (via the corpus luteum).


  • However, Human Chorionic Gonadotropin (hCG) is explicitly synthesized by the trophoblast cells of the developing embryo, and later by the fully formed placenta.


  • hCG signals the ovary to keep the corpus luteum alive, but the ovary itself does not produce it.


Why other options are incorrect:

Options A, B, and C are the definitive, textbook primary functions of the human ovaries.
#19 of 63 SZABMU 2023
Permalink
During menstrual cycle, after the female gamete is released from the ovary at ovulation, the remains of the follicle (corpus luteum) secretes:
A
FSH
B
LH
C
Testosterone
D
Progesterone
View Answer & Propolis Autopsy
Correct Key: Option D Diagnostic Explanation
Concept:

The post-ovulatory phase (luteal phase) is dedicated to preparing the uterus for pregnancy.

Solution:

  • Once the mature follicle expels the ovum, it collapses and is modified by LH into a glandular structure called the corpus luteum.


  • The primary role of this corpus luteum is to mass-produce progesterone.


  • Progesterone maintains and vascularizes the endometrial lining, ensuring it is thick and secretory in case a fertilized embryo arrives to implant.


Why other options are incorrect:

FSH and LH are pituitary hormones. While the corpus luteum secretes some estrogen, progesterone is its primary and defining product. Testosterone is predominantly a male hormone.
#20 of 63 ETEA 2023
Permalink
Fallopian tube is also known as:
A
Oviduct
B
Ovaries
C
Uterus
D
Cervix
View Answer & Propolis Autopsy
Correct Key: Option A Diagnostic Explanation
Concept:

Anatomical structures in the reproductive system often have multiple functional or historical names.

Solution:

  • The paired tubes that connect the ovaries to the uterus are responsible for catching the ovulated egg and providing a site for fertilization.


  • Because they conduct the ovum (egg), they are anatomically referred to as oviducts.


  • They are also commonly called Fallopian tubes or uterine tubes.


Why other options are incorrect:

Ovaries produce the eggs. The uterus is where the embryo implants and grows. The cervix is the lower, narrow opening of the uterus. None of these are alternate names for the Fallopian tube.
#21 of 63 NUMS 2023
Permalink
Which hormone induces labour pain?
A
Estrogen
B
Oxytocin
C
Progesterone
D
LH
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

Parturition (childbirth) relies on a powerful positive feedback loop driven by smooth muscle contraction.

Solution:

  • During labor, pressure on the cervix sends nerve impulses to the mother's brain.


  • The posterior pituitary gland responds by releasing large bursts of oxytocin.


  • Oxytocin stimulates the myometrium (uterine muscle) to contract powerfully. These intense muscular contractions are perceived as labor pains.


Why other options are incorrect:

Progesterone maintains pregnancy and actually inhibits uterine contractions. Estrogen prepares the uterus but does not cause acute labor pains. LH triggers ovulation.
#22 of 63 NUMS 2023
Permalink
The estrogen hormone secretion during the oogenesis is stimulated by:
A
Luteinizing hormone
B
Inhibin hormone
C
Follicle stimulating hormone
D
Testosterone hormone
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

Ovarian steroid production is regulated directly by anterior pituitary gonadotropins.

Solution:

  • At the start of the menstrual cycle, the anterior pituitary secretes Follicle Stimulating Hormone (FSH).


  • FSH targets the dormant primary follicles in the ovary, causing their granulosa cells to proliferate.


  • As the follicle grows under FSH stimulation, these cells begin to actively secrete estrogen.


Why other options are incorrect:

LH primarily stimulates ovulation and the formation of the corpus luteum (which secretes progesterone). Inhibin suppresses FSH. Testosterone is a male androgen.
#23 of 63 NUMS 2023
Permalink
Which of the following hormones of pituitary gland regulate the menstrual cycle?
A
Follicle stimulating hormone and estrogen
B
Luteinizing hormone and estrogen
C
Follicle stimulating hormone and luteinizing hormone
D
Estrogen and progesterone
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

The menstrual cycle is a downstream effect of brain-level endocrine control.

Solution:

  • The question specifically restricts the answer to hormones originating from the pituitary gland.


  • The anterior pituitary produces two gonadotropins: Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH).


  • These two hormones travel to the ovaries to orchestrate the entire cycle.


Why other options are incorrect:

Estrogen and progesterone are indeed primary regulators, but they are secreted by the ovaries, not the pituitary gland. Any option containing them fails the anatomical condition of the question.
#24 of 63 ETEA 2023
Permalink
The syphilis is a ____ disease.
A
Bacterial
B
Fungal
C
Protozoic
D
Viral
View Answer & Propolis Autopsy
Correct Key: Option A Diagnostic Explanation
Concept:

Sexually transmitted infections (STIs) are classified by their pathogenic origin to determine proper treatment (e.g., antibiotics vs. antivirals).

Solution:

  • Syphilis is an STI caused by the microorganism Treponema pallidum.


  • Treponema pallidum is a spirochete, which is a type of spiral-shaped bacterium.


  • Because it is a bacterial disease, syphilis can be effectively treated and cured with antibiotics like penicillin, especially in its early stages.


Why other options are incorrect:

It is not viral (like HIV or Herpes), fungal (like yeast infections), or protozoic (like Trichomoniasis).
#25 of 63 ETEA 2023
Permalink
The most common symptom of gonorrhea in males is:
A
Skin rash on neck
B
Joint pain
C
Painful urination
D
Chancre
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

Bacterial STIs heavily inflame the delicate mucous membranes of the urogenital tract.

Solution:

  • Gonorrhea is caused by the bacterium Neisseria gonorrhoeae, which predominantly infects the urethra in males.


  • This infection causes severe urethritis (inflammation of the urethra).


  • Consequently, the classic and most common symptom in males is a burning sensation or intensely painful urination, often accompanied by a purulent (pus-like) discharge.


Why other options are incorrect:

A "chancre" (painless ulcer) is the classic first sign of Syphilis, not Gonorrhea. While disseminated gonorrhea can cause joint pain or rashes, these are advanced complications, not the most common initial symptom.
#26 of 63 NUMS 2022
Permalink
In male reproductive system, the hormone involved in regulation of rate of spermatogenesis is called:
A
Luteinizing hormone
B
Follicle stimulating hormone
C
Testosterone
D
Inhibin
View Answer & Propolis Autopsy
Correct Key: Option D Diagnostic Explanation
Concept:

Negative feedback loops are essential for maintaining a constant rate of sperm production.

Solution:

  • When the rate of spermatogenesis is high, Sertoli cells within the seminiferous tubules secrete a peptide hormone called inhibin.


  • Inhibin travels to the anterior pituitary and directly inhibits the release of Follicle Stimulating Hormone (FSH).


  • By suppressing FSH, it slows down spermatogenesis to a normal, regulated rate.


Why other options are incorrect:

FSH and Testosterone stimulate spermatogenesis. LH stimulates testosterone production. While all are involved in the process, inhibin is the specific negative-feedback regulator that fine-tunes the rate.
#27 of 63 ETEA 2022
Permalink
The process of spermatogenesis (formation of sperm) takes place in which part of male reproductive system?
A
Urethra
B
Seminiferous tubules
C
Oviduct
D
Epididymis
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

Sperm cells require a highly specialized microenvironment to undergo meiosis and differentiate safely.

Solution:

  • Spermatogenesis takes place entirely within the walls of the seminiferous tubules located inside the testes.


  • These tubules are lined with germinal epithelium and supportive Sertoli cells that facilitate the entire developmental process from stem cell to mature sperm.


Why other options are incorrect:

The epididymis is for sperm storage and maturation (gaining motility), not formation. The urethra is the common passage for urine and semen. The oviduct is a part of the female reproductive system.
#28 of 63 ETEA 2022
Permalink
Which one of the following cells have haploid number of chromosomes?
A
Sperm cell
B
Mesophyll cell
C
Skin cell
D
Muscular cell
View Answer & Propolis Autopsy
Correct Key: Option A Diagnostic Explanation
Concept:

Gametes are reproductive cells produced by meiosis, containing half the genetic material of somatic cells.

Solution:

  • A human sperm cell is a male gamete.


  • Because it is produced via reductional division (meiosis), it contains a single set of chromosomes, making it haploid (\(n\)).


  • Upon fertilization with a haploid egg, the normal diploid (\(2n\)) number is restored in the zygote.


Why other options are incorrect:

Skin cells, muscular cells, and mesophyll cells (in plants) are all somatic (body) cells that undergo mitosis and remain diploid (\(2n\)).
#29 of 63 ETEA 2022
Permalink
The terminal portion of the male reproductive duct system is:
A
Vasa efferentia
B
Vasa deferens
C
Urethra
D
Epididymis
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

The male reproductive tract consists of a series of ducts that transport sperm from the testes to the exterior of the body.

Solution:

  • The pathway of sperm is: Seminiferous tubules \(\rightarrow\) Vasa efferentia \(\rightarrow\) Epididymis \(\rightarrow\) Vas deferens \(\rightarrow\) Ejaculatory duct \(\rightarrow\) Urethra.


  • The urethra acts as the final, terminal portion of the duct system, serving as a common passageway for both the excretory (urine) and reproductive (semen) systems in human males.


Why other options are incorrect:

Vasa efferentia, epididymis, and vasa deferens are all intermediate transport and storage ducts prior to reaching the urethra.
#30 of 63 BUMHS 2022
Permalink
Average sperm count per ml is:
A
2-10 million
B
20-150 thousand
C
20-150 million
D
2-10 thousand
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

A high volume of sperm is required in an ejaculate to ensure that at least a few survive the hostile environment of the female reproductive tract to reach the ovum.

Solution:

  • During ejaculation, about \(2\) to \(5 \text{ ml}\) of semen is expelled.


  • The average normal sperm concentration ranges from \(20\) to \(150 \text{ million}\) sperms per milliliter (ml).


  • A count below \(20 \text{ million}/\text{ml}\) is generally considered oligospermia and can lead to fertility issues.


Why other options are incorrect:

Counts in the thousands or below 10 million are clinically abnormally low and do not represent the healthy physiological average.
#31 of 63 DUHS 2022
Permalink
Uterus opens to the vagina by a narrow opening bounded by muscular sphincter at its bottom known as:
A
Urinary bladder
B
Cervix
C
Oviduct
D
Labia
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

The female reproductive system relies on muscular sphincters to isolate and protect the sterile environment of the uterus from the external environment.

Solution:

  • The cervix is the lower, narrow portion of the uterus.


  • It contains a strong muscular sphincter that forms a canal connecting the uterine cavity to the vagina.


  • Normally, this opening is blocked by a mucous plug to prevent infection, but it dilates during childbirth.


Why other options are incorrect:

The oviducts connect the ovaries to the top of the uterus. The urinary bladder is part of the excretory system. The labia are external genital structures.
#32 of 63 NUMS 2022
Permalink
During menstrual cycle, after the female gamete is release from the ovary (ovulation), the remains of the follicle secretes:
A
Progesterone
B
FSH
C
LH
D
Testosterone
View Answer & Propolis Autopsy
Correct Key: Option A Diagnostic Explanation
Concept:

The tissue left behind after ovulation undergoes luteinization to alter its primary secretory product.

Solution:

  • After releasing the egg, the ruptured follicle collapses and is transformed by LH into the corpus luteum.


  • The primary function of the corpus luteum is to secrete large amounts of progesterone (along with some estrogen).


  • This progesterone is vital for preparing the uterus for pregnancy.


Why other options are incorrect:

FSH and LH are secreted by the anterior pituitary, not the follicle. Testosterone is a male sex hormone (though trace amounts exist in females, it is not the primary secretion of the corpus luteum).
#33 of 63 NUMS 2022
Permalink
Normal gestation period in human is about ____ days.
A
300-320
B
320-350
C
270-280
D
240-250
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

Gestation is the period of intrauterine fetal development from conception to birth.

Solution:

  • In humans, the standard gestation period is universally recognized to be roughly 9 months.


  • Calculated from the first day of the last menstrual period (LMP), this is approximately 40 weeks, or \(280 \text{ days}\).


  • Calculated directly from fertilization, it is about 38 weeks, or \(266 \text{ days}\). The range \(270-280 \text{ days}\) accurately represents this timeline.


Why other options are incorrect:

240-250 days is significantly premature. Over 300 days is extremely post-term and medically abnormal.
#34 of 63 SZABMU 2022
Permalink
After fertilization zygote takes ____ for its journey from fallopian tube to uterus.
A
6-7 days
B
3-6 days
C
10-12 days
D
12-15 days
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

Early embryonic development involves cleavage cell divisions as the embryo physically travels toward the site of implantation.

Solution:

  • Fertilization occurs in the ampulla (upper third) of the fallopian tube.


  • Driven by the beating of cilia and peristaltic muscular contractions of the tube, the zygote begins its journey.


  • During this time, it divides into a morula and then a blastocyst, arriving in the uterine cavity after approximately 3 to 6 days.


Why other options are incorrect:

Implantation begins around day 6-7, but the journey to merely reach the uterus is shorter. Waiting 10-15 days would result in the blastocyst outgrowing its zona pellucida before reaching the necessary uterine environment.
#35 of 63 ETEA 2022
Permalink
The longest phase of the menstrual cycle is:
A
Pre-ovulatory phase
B
Secretary phase
C
Ovulatory phase
D
Menstrual phase
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

The menstrual cycle is divided into phases of varying lengths, but one phase has a remarkably consistent physiological duration.

Solution:

  • The menstrual phase lasts ~3-7 days.


  • The pre-ovulatory (proliferative) phase is variable, often lasting 7-10 days depending on the individual.


  • The secretory (luteal) phase is structurally the longest and most consistent phase, lasting exactly 14 days in almost all women, driven by the lifespan of the corpus luteum.


Why other options are incorrect:

The ovulatory phase is extremely brief (1-2 days). The menstrual and pre-ovulatory phases are generally shorter than 14 days.
#36 of 63 BUMHS 2022
Permalink
Corpus luteum secretes the hormones:
A
Testosterone
B
Parathormone
C
Oxytocin
D
Progesterone
View Answer & Propolis Autopsy
Correct Key: Option D Diagnostic Explanation
Concept:

The corpus luteum acts as a temporary endocrine gland vital for early pregnancy maintenance.

Solution:

  • Following ovulation, the remnants of the follicle cells absorb lipids and become the corpus luteum.


  • Its primary function is the prolific secretion of progesterone.


  • This hormone halts further endometrial proliferation and initiates secretory changes, making the uterus a plush environment for implantation.


Why other options are incorrect:

Testosterone is a male hormone. Parathormone regulates blood calcium. Oxytocin drives uterine contractions. None of these are produced by the corpus luteum.
#37 of 63 DUHS 2022
Permalink
The vacated vesicular follicle forms a fatty yellow structure on ovary called as:
A
Graafian luteum
B
Corpus luteum
C
Ruptured ovum
D
Follicle
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

Follicle morphology changes dramatically once the oocyte is expelled.

Solution:

  • Once the mature (vesicular or Graafian) follicle ruptures and releases the egg, the remaining granulosa and theca cells collapse inward.


  • Under the influence of Luteinizing Hormone (LH), these cells accumulate a yellow pigment called lutein.


  • This newly formed, fatty, yellow glandular mass is anatomically termed the corpus luteum.


Why other options are incorrect:

"Graafian luteum" is a mixed, fabricated term. A ruptured ovum refers to the egg itself, not the follicle. It is no longer just a standard "follicle" once luteinized.
#38 of 63 BUMHS 2022
Permalink
Treponema pallidum is the causative organism for which disease?
A
Gonorrhea
B
Syphilis
C
AIDS
D
Diabetes
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

Sexually Transmitted Infections (STIs) are caused by specific bacterial or viral pathogens.

Solution:

  • Treponema pallidum is a spiral-shaped bacterium (spirochete).


  • It is the exclusive causative agent of the sexually transmitted disease Syphilis.


  • Syphilis progresses in stages, starting with a painless sore (chancre) and potentially leading to severe neurological and cardiovascular issues if untreated.


Why other options are incorrect:

Gonorrhea is caused by the bacterium Neisseria gonorrhoeae. AIDS is caused by the Human Immunodeficiency Virus (HIV). Diabetes is a metabolic disorder, not an infectious disease.
#39 of 63 PMC 2020
Permalink
Which one of the following represents the changes that occur in the ovary and the uterus approximately every 28 days involving ovulation with the breakdown and loss of the lining of the uterus?
A
Ovulation
B
Uterine cycle
C
Menstrual cycle
D
Embryo formation
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

Human female reproduction involves coordinated, cyclic changes in multiple organ systems simultaneously.

Solution:

  • The term that encompasses both the cyclical changes in the ovary (ovarian cycle: follicle maturation, ovulation) and the cyclical changes in the uterus (uterine cycle: thickening, breakdown, and bleeding) is the menstrual cycle.


  • This cycle averages 28 days in length.


Why other options are incorrect:

The uterine cycle only refers to endometrial changes. Ovulation is a single event, not the entire cycle. The menstrual cycle broadly defines the entire interconnected 28-day physiological process.
#40 of 63 PMC 2020
Permalink
Which of the following hormones of the pituitary gland regulate the menstrual cycle?
A
Follicle stimulating hormone and estrogen
B
Luteinizing hormone and estrogen
C
Follicle stimulating hormone and Luteinizing hormone
D
Estrogen and progesterone
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

The menstrual cycle is driven from the "top down" by hormones originating in the brain.

Solution:

  • The question specifically asks for hormones of the pituitary gland.


  • The anterior pituitary gland secretes two key gonadotropins: Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH).


  • FSH drives the follicular phase, and LH drives ovulation and the luteal phase.


Why other options are incorrect:

Estrogen and Progesterone are indeed primary regulators of the menstrual cycle, but they are secreted by the ovaries, not the pituitary gland.
#41 of 63 MDCAT 2019
Permalink
During spermatogenesis, the ____ which are haploid cells eventually mature into spermatozoa/mature sperms?
A
Secondary spermatocytes
B
Spermatogonia
C
Primary spermatocytes
D
Spermatids
View Answer & Propolis Autopsy
Correct Key: Option D Diagnostic Explanation
Concept:

Maturation of sperm involves extensive morphological remodeling of already haploid cells.

Solution:

  • At the end of Meiosis II, haploid cells called spermatids are formed.


  • These spermatids are round and non-motile. They undergo a morphological transformation known as spermiogenesis (shedding excess cytoplasm, forming a tail) to eventually mature into spermatozoa.


Why other options are incorrect:

Spermatogonia and primary spermatocytes are diploid. Secondary spermatocytes are haploid but must first undergo Meiosis II to become spermatids before structural maturation can occur.
#42 of 63 MDCAT 2019
Permalink
Which hormonal pair would maintain the endometrium and make it receptive for implantation of embryo?
A
Luteinizing Hormone and Progesterone
B
Estrogen and Follicle Stimulating Hormone
C
Luteinizing Hormone and Follicle Stimulating Hormone
D
Estrogen and Progesterone
View Answer & Propolis Autopsy
Correct Key: Option D Diagnostic Explanation
Concept:

Successful embryo implantation requires the combined, sequential actions of the primary ovarian steroid hormones.

Solution:

  • Estrogen is responsible for the initial proliferation and rebuilding of the endometrial lining (thickening).


  • Progesterone follows up by vascularizing the lining, making it secretory, spongy, and highly receptive.


  • Together, this pair of hormones synergistically maintains a stable, nutrient-rich uterine environment essential for embryo implantation.


Why other options are incorrect:

FSH and LH are pituitary hormones that act on the ovaries to cause the release of estrogen and progesterone, rather than acting directly on the uterine endometrium themselves.
#43 of 63 MDCAT 2019
Permalink
Which of the following hormone stimulates the ovulation from the follicle into oviduct?
A
Luteinizing hormone
B
Estrogen
C
Follicle stimulating hormone
D
Progesterone
View Answer & Propolis Autopsy
Correct Key: Option A Diagnostic Explanation
Concept:

The physical release of the egg requires an acute biochemical trigger mid-cycle.

Solution:

  • The surge of Luteinizing Hormone (LH) from the anterior pituitary directly targets the mature Graafian follicle in the ovary.


  • It induces proteolytic enzymes that digest the follicle wall, resulting in the rupture and release of the secondary oocyte into the fallopian tube (oviduct). This process is ovulation.


Why other options are incorrect:

FSH develops the follicle. Estrogen thickens the uterus. Progesterone maintains the uterus post-ovulation. Only LH is the acute trigger for the actual ovulatory event.
#44 of 63 AJK 2019
Permalink
On the onset of puberty in the females, the pituitary gland releases the:
A
Progesterone
B
Luteinizing hormone
C
Oxytocin
D
Follicle stimulating hormone
View Answer & Propolis Autopsy
Correct Key: Option D Diagnostic Explanation
Concept:

Puberty in females is marked by the initiation of the first menstrual cycles (menarche), which requires the waking up of the dormant ovaries.

Solution:

  • At the onset of puberty, the hypothalamus begins secreting GnRH, which signals the anterior pituitary gland.


  • The pituitary responds by primarily releasing Follicle Stimulating Hormone (FSH) into the bloodstream.


  • FSH arrives at the ovaries and stimulates dormant primary follicles to begin growing, thus starting the very first ovarian cycles.


Why other options are incorrect:

While LH is also released, FSH is universally recognized as the primary hormone responsible for initiating the development of follicles at puberty. Progesterone is from the ovaries. Oxytocin is for labor/lactation.
#45 of 63 AJK 2019
Permalink
Secretion of FSH is inhibited by:
A
Testosterone
B
Estrogen
C
Aldosterone
D
LH
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

The female reproductive cycle heavily relies on negative feedback mechanisms to prevent the simultaneous maturation of too many follicles.

Solution:

  • As a follicle grows under the influence of FSH, it secretes increasing amounts of estrogen.


  • Moderate levels of estrogen circulating in the blood exert a negative feedback effect on the anterior pituitary gland.


  • This explicitly inhibits the further secretion of FSH, ensuring that only the most dominant follicle survives and no new follicles begin maturing mid-cycle.


Why other options are incorrect:

Aldosterone regulates sodium/water balance. Testosterone is the primary male hormone (though inhibin and testosterone inhibit FSH in males, estrogen is the primary inhibitor during the female follicular phase). LH does not inhibit FSH.
#46 of 63 ETEA 2019
Permalink
Progesterone is secreted by:
A
Ripening follicles
B
Corpus luteum
C
Uterine epithelium
D
Fertilized egg
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

Post-ovulation, the empty follicle undergoes a physical and biochemical transformation to support a potential pregnancy.

Solution:

  • After the egg is released, LH acts on the remaining follicular cells, transforming them into a temporary yellow endocrine gland called the corpus luteum.


  • The primary function of this corpus luteum is the massive secretion of the hormone progesterone, which maintains the uterine lining.


Why other options are incorrect:

Ripening follicles secrete primarily estrogen. The uterine epithelium responds to progesterone but doesn't secrete it. The fertilized egg (embryo) later secretes hCG, not progesterone directly.
#47 of 63 MDCAT 2018
Permalink
Which hormone is released in female in response to FSH from pituitary gland?
A
Oxytocin
B
Estrogen
C
ADH
D
Progesterone
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

The hypothalamic-pituitary-gonadal axis relies on a chain of signaling hormones.

Solution:

  • Follicle Stimulating Hormone (FSH) from the anterior pituitary targets the ovaries.


  • Specifically, FSH stimulates the granulosa cells surrounding the growing primary and secondary follicles.


  • In response to this stimulation, these follicular cells synthesize and secrete estrogen into the bloodstream.


Why other options are incorrect:

Progesterone is released primarily in response to LH forming the corpus luteum. Oxytocin and ADH are released from the posterior pituitary and are not regulated by FSH.
#48 of 63 MDCAT 2018
Permalink
Which of the following hormone acts on the uterus wall for thickening?
A
Zona pellucida
B
Oxytocin
C
Progesterone
D
Follicle stimulating hormone
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

The endometrium must be physically thickened and enriched to support a developing embryo.

Solution:

  • During the secretory phase of the menstrual cycle, the corpus luteum secretes large volumes of progesterone.


  • Progesterone acts directly on the endometrial wall of the uterus, causing the glands to grow, blood vessels to proliferate, and the tissue to become highly thick, spongy, and nutrient-rich.


Why other options are incorrect:

FSH acts on the ovaries, not the uterus. Oxytocin causes uterine contractions during labor, not thickening. The zona pellucida is a glycoprotein layer surrounding the ovum, not a hormone.
#49 of 63 MDCAT 2017
Permalink
FSH stimulates the production of estrogen hormone which has two targets ____ and ____
A
Uterus, posterior pituitary
B
Uterus, anterior pituitary
C
Ovaries, uterus
D
Ovaries, hypothalamus
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

Estrogen produced by the developing follicle exerts effects locally on the reproductive organs and systemically.

Solution:

  • Estrogen has dual primary targets directly tied to facilitating the current cycle.


  • Target 1 (Ovaries): Estrogen acts locally to assist in the continued maturation of the dominant ovarian follicle.


  • Target 2 (Uterus): Estrogen travels via the bloodstream to the uterus, where it powerfully stimulates the rebuilding and vascularization of the endometrium (proliferative phase).


Why other options are incorrect:

While estrogen does exert feedback on the anterior pituitary and hypothalamus, in the context of the standard biological reproductive physiology curriculum referenced by the key, its primary structural/functional reproductive targets are defined as the ovaries (follicle maturation) and the uterus (endometrial proliferation).
#50 of 63 MDCAT 2017
Permalink
Which of the following hormone suppresses ovulation?
A
Progesterone
B
FSH
C
Insulin
D
Prolactin
View Answer & Propolis Autopsy
Correct Key: Option A Diagnostic Explanation
Concept:

During the luteal phase and pregnancy, it is necessary to prevent the release of additional eggs.

Solution:

  • Progesterone is secreted by the corpus luteum (and later the placenta).


  • High circulating levels of progesterone exert a strong negative feedback on the hypothalamus and anterior pituitary.


  • This suppression prevents the release of FSH and the LH surge. Without an LH surge, subsequent follicle maturation and ovulation are entirely suppressed.


Why other options are incorrect:

FSH promotes follicle development. Insulin regulates blood glucose. Prolactin promotes milk production (though very high prolactin can indirectly suppress ovulation, progesterone is the primary physiological cycle regulator).
#51 of 63 MDCAT 2017
Permalink
Which of the following hormone causes ovulation?
A
LH
B
Estrogen
C
Progesterone
D
FSH
View Answer & Propolis Autopsy
Correct Key: Option A Diagnostic Explanation
Concept:

Ovulation is a sudden, mechanically violent event requiring a specific hormonal spike.

Solution:

  • Around day 14 of a standard 28-day cycle, the anterior pituitary releases a massive spike of Luteinizing Hormone (LH).


  • This LH surge triggers a cascade of enzymatic reactions that weaken the wall of the mature Graafian follicle.


  • The follicle ruptures, expelling the secondary oocyte into the fallopian tube. Thus, LH causes ovulation.


Why other options are incorrect:

FSH stimulates initial follicle growth. Estrogen prepares the uterus and triggers the LH surge, but doesn't directly rupture the follicle. Progesterone maintains the uterine lining post-ovulation.
#52 of 63 MDCAT 2016
Permalink
Events of menstrual cycle are regulated by the:
A
Ethylene
B
Auxins
C
Gonadotrophins
D
Gibberellins
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

The human reproductive cycle is orchestrated by complex hormonal interplay originating from the brain.

Solution:

  • The menstrual cycle is fundamentally regulated by hormones released from the anterior pituitary gland, specifically FSH (Follicle Stimulating Hormone) and LH (Luteinizing Hormone).


  • Because these hormones target the gonads (ovaries), they are collectively known as gonadotrophins (or gonadotropins).


Why other options are incorrect:

Ethylene, auxins, and gibberellins are all highly specific plant hormones involved in plant growth, ripening, and tropisms, and play no role in human reproduction.
#53 of 63 MDCAT 2016
Permalink
Decrease of FSH and increase of estrogen cause pituitary gland to secrete:
A
Somatotrophin
B
Testosterone
C
Luteinizing hormone
D
Spermatogonium
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

The mid-cycle hormonal shift relies on a switch from negative to positive feedback by estrogen.

Solution:

  • During the late follicular phase, the dominant follicle secretes exceptionally high levels of estrogen.


  • While moderate estrogen inhibits FSH, peak estrogen levels exert a positive feedback effect on the anterior pituitary.


  • This sudden positive feedback triggers a massive surge in the secretion of Luteinizing Hormone (LH), which is the direct trigger for ovulation.


Why other options are incorrect:

Somatotrophin is growth hormone. Testosterone is primarily a male hormone. Spermatogonium is a male germ cell, not a hormone.
#54 of 63 MDCAT 2015
Permalink
In females, FSH stimulates the ovary to produce:
A
Progesterone
B
Prolactin
C
Estrogen
D
Oxytocin
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

The development of ovarian follicles induces the production of female sex hormones to prepare the body for potential reproduction.

Solution:

  • Follicle Stimulating Hormone (FSH) promotes the growth of the Granulosa cells surrounding the developing oocyte within the follicle.


  • As the follicle grows under FSH influence, these follicular cells secrete increasing amounts of estrogen into the bloodstream.


  • Estrogen then drives the proliferative phase of the uterine endometrium.


Why other options are incorrect:

Progesterone is primarily produced by the corpus luteum later under the influence of LH. Prolactin and Oxytocin are involved in lactation and childbirth and are released from the pituitary gland.
#55 of 63 MDCAT 2015
Permalink
The oocyte released during ovulation is in:
A
Anaphase I
B
Metaphase I
C
Prophase I
D
Metaphase II
View Answer & Propolis Autopsy
Correct Key: Option D Diagnostic Explanation
Concept:

Oogenesis in human females features strict cell cycle arrests at specific meiotic stages.

Solution:

  • A primary oocyte completes Meiosis I just before ovulation to become a secondary oocyte.


  • The secondary oocyte immediately begins Meiosis II but is arrested at Metaphase II.


  • It is precisely in this arrested Metaphase II stage that the ovum is released from the ovary during ovulation.


  • Meiosis II will only resume and complete if fertilization by a sperm occurs.


Why other options are incorrect:

Primary oocytes are arrested in Prophase I from birth until puberty. Anaphase I and Metaphase I are brief transitional phases occurring just prior to ovulation.
#56 of 63 MDCAT 2015
Permalink
In which phase of human female menstrual cycle, endometrium prepares for the implantation of embryo?
A
Proliferative phase
B
Menstrual phase
C
Secretory phase
D
Ovulation phase
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

The endometrium undergoes cyclic changes to create a highly hospitable environment for a potential embryo.

Solution:

  • After ovulation, the menstrual cycle enters the secretory phase (also known as the luteal phase).


  • During this time, the corpus luteum secretes large amounts of progesterone.


  • Progesterone causes the endometrium to become highly vascularized, thick, and spongy. Endometrial glands secrete glycogen-rich fluids to nourish and prepare for the implantation of a blastocyst.


Why other options are incorrect:

The proliferative phase only rebuilds the lining after menstruation. The menstrual phase involves shedding the lining. Ovulation is simply the release of the egg.
#57 of 63 MDCAT 2014
Permalink
Yellowish glandular structure formed after the release of egg from follicle is called:
A
Corpus callosum
B
Corpus luteum
C
Graffian follicle
D
Follicle atresia
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

Following ovulation, the remnants of the ovarian follicle transform into a temporary endocrine gland.

Solution:

  • Under the influence of Luteinizing Hormone (LH), the ruptured Graafian follicle collapses and its cells enlarge, accumulating a yellow lipid pigment.


  • This modified structure is called the corpus luteum (Latin for "yellow body").


  • It begins secreting large amounts of progesterone to maintain the uterine lining for potential pregnancy.


Why other options are incorrect:

The Graafian follicle is the pre-ovulatory structure. Follicle atresia is the degeneration of unselected follicles. The corpus callosum is a brain structure connecting the two cerebral hemispheres.
#58 of 63 MDCAT 2014
Permalink
On puberty, the development of primary follicles is stimulated by:
A
ICSH
B
LH
C
FSH
D
Estrogen
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

The onset of the ovarian cycle at puberty is triggered by gonadotropins released from the anterior pituitary.

Solution:

  • At puberty, the anterior pituitary begins to secrete Follicle Stimulating Hormone (FSH).


  • As the name implies, FSH acts directly on the ovaries to stimulate the growth and development of several primary follicles each month.


  • Usually, only one of these follicles will reach full maturity.


Why other options are incorrect:

LH (and its male equivalent ICSH) is primarily responsible for triggering ovulation and forming the corpus luteum later in the cycle. Estrogen is produced by the developing follicles in response to FSH.
#59 of 63 MDCAT 2013
Permalink
What is the location of interstitial cells in testes?
A
Inside the seminiferous tubules
B
Among the germinal epithelial cells
C
Around the testes
D
Between the seminiferous tubule
View Answer & Propolis Autopsy
Correct Key: Option D Diagnostic Explanation
Concept:

The structural anatomy of the testes separates the site of sperm development from the site of hormone production.

Solution:

  • The testes are packed with highly coiled seminiferous tubules where sperm develop.


  • The spaces between the seminiferous tubules contain connective tissue, blood vessels, and specialized endocrine cells called interstitial cells (Leydig cells).


  • This strategic location allows the testosterone produced by these cells to easily enter the bloodstream and also directly influence adjacent seminiferous tubules.


Why other options are incorrect:

Sertoli and germ cells are located inside the seminiferous tubules. Leydig cells are explicitly defined by their "interstitial" (in-between) positioning.
#60 of 63 MDCAT 2013
Permalink
Spermatogonia differentiate directly into:
A
Primary spermatocytes
B
Spermatozoa
C
Secondary spermatocytes
D
Spermatids
View Answer & Propolis Autopsy
Correct Key: Option A Diagnostic Explanation
Concept:

The progression of spermatogenesis moves from diploid stem cells to haploid gametes through specific developmental stages.

Solution:

  • Type B spermatogonia (diploid cells) undergo a period of growth and differentiation.


  • They enlarge and prepare for the first meiotic division, directly becoming diploid primary spermatocytes.


Why other options are incorrect:

Primary spermatocytes must undergo Meiosis I to become secondary spermatocytes. Secondary spermatocytes undergo Meiosis II to become spermatids, which then differentiate into spermatozoa. Spermatogonia do not jump straight to these later stages.
#61 of 63 MDCAT 2011
Permalink
A type of cell in human testes which produces testosterone is called:
A
Sertoli cells
B
Germ cells
C
Spermatocytes
D
Interstitial cells
View Answer & Propolis Autopsy
Correct Key: Option D Diagnostic Explanation
Concept:

The testes serve a dual function: spermatogenesis (sperm production) and steroidogenesis (hormone production).

Solution:

  • Interstitial cells (also known as Leydig cells) are located in the connective tissue spaces between the seminiferous tubules.


  • Under the stimulation of Luteinizing Hormone (LH / ICSH), these cells synthesize and secrete the primary male sex hormone, testosterone.


Why other options are incorrect:

Sertoli cells provide nourishment and support for developing sperm but do not produce testosterone. Germ cells and spermatocytes are stages in the sperm development pathway.
#62 of 63 MDCAT 2011
Permalink
Which one of the following differentiates directly into mature sperm?
A
Primary spermatocyte
B
Spermatid
C
Spermatogonia
D
Secondary spermatocyte
View Answer & Propolis Autopsy
Correct Key: Option B Diagnostic Explanation
Concept:

Spermiogenesis is the final stage of spermatogenesis, where major structural changes occur without cell division.

Solution:

  • After meiosis II, the resulting haploid cells are called spermatids.


  • A spermatid is initially a spherical, non-motile cell.


  • Through a morphological differentiation process called spermiogenesis, it develops an acrosome, condenses its nucleus, and forms a flagellum (tail) to become a highly motile, mature spermatozoon (sperm).


Why other options are incorrect:

Spermatogonia and primary/secondary spermatocytes must first complete meiosis before they can reach the spermatid stage to begin physical differentiation.
#63 of 63 MDCAT 2010
Permalink
The first cells produced by the repeated cell division of germinal epithelium of testis are:
A
Interstitial cells
B
Secondary spermatocytes
C
Spermatogonia
D
Spermatids
View Answer & Propolis Autopsy
Correct Key: Option C Diagnostic Explanation
Concept:

Spermatogenesis begins in the outermost layer of the seminiferous tubules with undifferentiated germ cells.

Solution:

  • The germinal epithelium of the testis is lined with diploid stem cells.


  • These stem cells undergo repeated mitotic divisions to produce spermatogonia (singular: spermatogonium) at an early stage.


  • These spermatogonia will eventually grow into primary spermatocytes.


Why other options are incorrect:

Secondary spermatocytes and spermatids are formed much later via meiosis. Interstitial cells (Leydig cells) are located outside the seminiferous tubules and do not develop from the germinal epithelium; they are responsible for producing testosterone.
The Complete Combat Engine

Ready to Score 180+ in MDCAT 2026?

Join thousands of pre-med students utilizing BeambePrep's full combat suite: Swarm Mode timed challenges, Normal Grind Mode, Propolis Ward mistake notebooks, Infinite Full-Length Practice (FLP) Mocks, and FSRS Spaced Repetition.