PMDC Verified Question 12 of 47
After the digestion & before absorption the product of the protein is:
A
Only Amino Acid
B
Amino acid and small polypeptide
C
Only small polypeptide
D
Only ammonia
Tap any option to test your recall and reveal the step-by-step Propolis autopsy.

Propolis Cognitive Error Autopsy

Official Correct Choice:
Option B: Amino acid and small polypeptide
Concept:

Protein digestion is a gradual enzymatic process occurring mainly in the stomach and small intestine, utilizing endopeptidases and exopeptidases.

Formula:

$$ \text{Protein} \xrightarrow{\text{Proteases}} \text{Small Peptides} + \text{Amino Acids} $$

Solution:

  • By the time dietary proteins reach the brush border of the small intestine for absorption, pancreatic and gastric proteases have aggressively cleaved them.
  • However, they are not strictly reduced to single amino acids; rather, the intestinal lumen contains a mixture of free amino acids and small polypeptides (dipeptides and tripeptides).
  • These di- and tripeptides are absorbed by enterocytes alongside free amino acids.


Why other options are incorrect:

Digestion does not perfectly yield 'only' amino acids in the lumen before absorption. Conversely, saying it is 'only' polypeptides ignores the massive amount of free amino acids produced. Ammonia is a metabolic waste product of deamination in the liver, not a product of digestive tract hydrolysis.

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